Waters offers a comprehensive range of analytical system solutions, software, and services for scientists. Liquid Chromatography. Mass Spectrometry. Waters is the leading provider of lab equipment, supplies and software for scientists across the world. Easily research and order everything your lab needs! Waters offers a comprehensive range of analytical system solutions, software, and services for scientists. Liquid Chromatography. Mass Spectrometry. Waters is the leading provider of lab equipment, supplies and software for scientists across the world. Easily research and order everything your lab needs!

Symmetry Columns

Exceed the standards for an HPLC Column

Symmetry^® LC Columns are manufactured using high purity silica and tightly controlled manufacturing processes to ensure that you receive a column that exceeds the standards for HPLC column performance. No other silica-based LC column brand can match the column-to-column and batch-to-batch reproducibility of the Symmetry family. Symmetry Columns are available in column, cartridge, and guard formats to include:

Symmetry C₁₈ and C₈ chromatography columns that deliver maximum reproducibility
SymmetryShield RP18 and RP8 chromatography columns to provide superior peak shape
Symmetry300 C₁₈ and C₄ chromatography columns, which offer high recoveries of peptides and proteins

Extend column lifetime with VanGuard Column Protection Products

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Symmetry Column Characteristics

Symmetry HPLC Columns for Reproducibility

You can rely on a Symmetry HPLC column for rugged and reproducible performance. Narrow column specification ranges minimize variation giving you the confidence that the methods you use today will continue to be used in the future.

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Symmetry Shield Columns for Superior Peak Shape

SymmetryShield™ Columns feature Waters' patented embedded polar group technology that shields the silica's residual silanols from highly basic analytes at improves overall peak shape. Additionally, by placing the embedded polar group close to the silica surface, the activity of the surface silanols is further reduced. This imparts selectivity and retention that is different compared to the Symmetry C₁₈ ligand.

Embedded polar group technology improves chromatographic peak shape and selectivity.

Symmetry300 Columns Deliver High Peptide Recovery

All Symmetry300™ columns are QC tested with peptide samples to ensure exceptional batch-to-batch reproducibility. These wide-pore (300Å), reversed-phase chromatography columns deliver superior performance when simultaneously separating hydrophilic and hydrophobic peptides, as well as neutral and highly basic peptides. Expect better performance using either high or low mass loads with a Symmetry300 column.

Symmetry300 C₄ Columns provide superior peptide separation.

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Minimal Chromatographic Effects with VanGuard Cartridges

VanGuard Column Protection

The often complex sample matrices encountered in pharmaceutical, natural product, environmental, and industrial chemical analysis prematurely shorten analytical column lifetime and degrade chromatographic performance. Waters VanGuard Cartridge Columns help improve analytical column performance by removing particulate and chemical contamination that may be present in the mobile-phase stream—without compromising chromatographic performance.