HPLC Columns

State-of-the-art Reversed-Phase and HILIC HPLC Columns

Waters offers a wide range of analytical and preparative chromatography columns to meet the needs of virtually every application. The Waters Column Advisor recommends the most appropriate column depending on the on the application requirements you need to consider and the column characteristics you are looking for. Separations developed on our analytical columns can be directly scaled up to preparative columns. We supply a wide range of phase chemistries in numerous column dimensions for preparative work to meet your scale-up needs. All chromatography columns meet stringent specifications to ensure excellent performance and column-to-column reproducibility. We also offer a wide range of accessoriesto support these columns.


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CORTECS Columns Solid-core particle technology in 1.6 µm and 2.7 micron enables new levels of efficiency and performance in HPLC, UHPLC and UPLC. Chemistries include C18, C18+, T3, C8, Shield RP18, Phenyl & HILIC.
XBridge Columns XBridge BEH Columns for UHPLC/HPLC for high pH HPLC, and other extreme conditions, ideal for method development. Chemistries include C18, C8, Shield RP18, Phenyl, HILIC & Amide.
XSelect Columns CSH and HSS Columns improve selectivity and offers the highest performance for basic compounds in the acidic, low ionic strength mobile phases for HPLC. CSH chemistries are C18, Phenyl-Hexyl, Fluoro-Phenyl, for HSS, C18, C18 SB, T3, PFP, Cyano.
VanGuard Column Protection VanGuard Pre-columns and cartridges for prolonging analytical HPLC column lifetime while maintaining chromatographic performance.
UHPLC Columns Our focused selection of UHPLC columns highlight the performance advantages modern UHPLC instrumentation.
Symmetry Columns HPLC columns with high purity silica and tightly controlled manufacturing processes to ensure batch to batch reproducibility and superior peak shapes. Chemistries include C18, C4, C8, Shield RP18, Shield RP8.
Bioseparations Columns & Consumables Chemistry consumables for the accurate analysis of peptides, proteins, oligonucleotides, glycans and amino acids.
Atlantis and Atlantis PREMIER Columns Analytical and preparative HPLC columns for stable polar compound retention of broad analyte mixtures.
SunFire Columns Chromatography columns in analytical / preparative dimensions and designed for high mass loading capability, low pH stability, and high efficiency. Chemistries include C18 and C8.
XTerra Columns Analytical and preparative LC columns for high pH drug discovery, method development and purification separations. Chemistries include C18, C8 and Phenyl.
Nova-Pak Columns Columns that offer high resolution as well as faster and more efficient chromatography. Chemistries include C18, C8, Cyano, and Phenyl.
Waters Spherisorb Columns Columns for different and unique separation selectivities, widely published for analytical and preparative HPLC. Chemistries include C18, Amino (NH2), C1, C6, C8, Cyano (CN), Phenyl, SAX, SCX, ODS1, and ODS2.
Resolve Columns Non-end capped columns providing high retention of polar compounds and high resolution. Chemistries include C18, C8 and Cyano (CN).
µBondapak - Bondapak Ideal for the separation of acidic, basic, and neutral compounds making them widely useful for preparative chromatography. Chemistries include C18, Phenyl, Cyano (CN), and NH2.
µPorasil/Porasil Columns QC tool for scalability for preparative high performance liquid chromatography.
Waters PAH Columns For improved analysis of PAH Polyaromatic hydrocarbons (PAHs) compounds. Chemistries include C18.
Protein-Pak Columns HPLC IEX, HIC, Affinity HPLC-based columns intended for high-quality analysis or lab scale isolation of proteins or polypeptides. Chemistries include affintiy, anion-exchange, cation-exchange, SAX, and SEC.
Shodex RSPak Columns Polymeric reversed-phase columns for applications requiring broad pH range (2-12) ideal for basic compounds as well as different selectivity from silica-based columns. Chemistries include DE-613.
BioSuite Columns HPLC columns ideally suited for the isolation, analysis, and characterization of proteins and peptides. Chemistries include C18, anion-exchange, cation-exchange, high resolution SEC, Phenyl, SEC and ultra high resolution SEC.
Column Accessories Waters offers a variety of tubings, fittings, column connections, and replacement parts for columns and cartridges.

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