SunFire Columns

Superior Peak Shape and Efficiency

SunFire Chromatography Columns are available in analytical and preparative dimensions and feature state-of-the-art bonded-silica designed for high mass loading capability, excellent low pH stability, superior peak shapes, and high efficiency.

With a wide variety of particle sizes from 2.5 µm to 10 µm and C18 and C8 column chemistries, SunFire columns offer greater flexibility in selecting silica-based HPLC columns. For preparative applications, SunFire silica is available in 5 and 10 µm particle sizes.

Extend column lifetime with VanGuard Protection

Scale-up your analytical LC with OBD Prep Columns

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In this comparison test of columns packed with 5 μm particles, the SunFire C18 column has the lowest USP tailing factor for the basic probe amitriptyline under demanding pH 7 mobile phase conditions.

Analytical Separation

SunFire Chromatography Columns provide symmetrical peak shapes for improved resolution. With new bonding and endcapping technologies, they offer exceptional efficiency for acid, neutral, and basic compounds at low and intermediate pH ranges. SunFire columns are packed with state-of-the-art silica and new proprietary C18 and C8 bonding and endcapping for high efficiency, resulting in greater sensitivity. SunFire columns are compatible with mass spectrometry applications, providing sharp peaks, high sensitivity, large peak capacities and very low bleed. Chromatography column lifetime is improved through superior low pH stability compared to many silica HPLC column brands.

VanGuard Column Protection

The often complex sample matrices encountered in pharmaceutical, natural product, environmental, and industrial chemical analysis prematurely shorten analytical column lifetime and degrade chromatographic performance. Waters VanGuard Cartridge Columns help improve analytical column performance by removing particulate and chemical contamination that may be present in the mobile-phase stream—without compromising chromatographic performance.

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Minimal Chromatographic Effects with VanGuard Cartridges

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Isolation of Nimodipine and its impurities

Preparative

The Optimum Bed Density (OBD) design used in SunFire Columns delivers the most reliable and consistent preparative column performance. SunFire Prep OBD Columns exhibit optimum column efficiencies and lifetime through extended usage of over 1000 DMSO injections. SunFire Prep OBD Columns ensure equivalent chromatographic performance from analytical to preparative dimensions, eliminating the need for subsequent method re-development. SunFire Prep particles and columns are manufactured in a cGMP environment, under tight synthesis and column packing controls, ensuring accurate scale-up capability.

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Available in 5 µm and 10 µm Particle Sizes

SunFire Prep Columns, exhibit excellent column life and stability due to the OBD design, as well as excellent peak shapes and high mass loading. SunFire Prep silica particles have been intentionally synthesized to deliver high mass loadability under acidic to moderate pH mobile phase conditions. The high mass loading of SunFire materials facilitates the use of smaller preparative column dimensions. By increasing the sample load, SunFire may provide increased sensitivity when detecting and quantifying low levels of analytes, impurities and degradants.

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OBD: Optimum Bed Density Preparative Columns

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Normal-Phase Purification

SunFire normal-phase silica columns purify analytes that cannot be separated in reversed-phase liquid chromatography, such as highly hydrophilic analytes, analytes that are unstable in water. They offer: