Protein-Pak HR Ion-Exchange Glass Columns

Protein-Pak HR packing materials are based on rigid, hydrophilic, polymethacrylate particles with large 1000 Å pores. The naturally hydrophilic polymer reduces non-specific adsorption, resulting in quantitative recovery of protein mass and bioactivity. These packings are compatible with buffers in the pH range 2-12, and will withstand exposure to caustic solutions.

Protein-Pak HR ion exchangers are available with a:

• Q functional group, a strong anion exchanger
• DEAE, a weak anion exchanger
• SP a strong cation exchanger
• CM, a weak cation exchanger

The Protein-Pak HR 8 µm and 15 µm packing materials are available prepacked in Waters Advanced Purification (AP) glass columns. These columns are compatible with a variety of analytical and preparative LC instrumentation.

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BioSuite Ion-Exchange HPLC Columns

BioSuite Ion-Exchange Columns include four separation chemistries -- SP strong and CM weak cation-exchangers and Q strong and DEAE weak anion-exchangers -- bonded to a pH stable (pH 2–12), methacrylic ester-based polymeric resin.  This broad choice of separation chemistries provides chromatographers with the flexibility to develop methods that separate proteins or peptides based on subtle charge differences.  Selected BioSuite ion-exchange columns are also offered with PEEK hardware as well as in 21.5 mm I.D. for lab-scale preparative applications.