The spatial distribution of molecular species in a sample is crucial to gaining key insight into biological, chemical and physiological processes. Mass spectrometry imaging (MSI) with Desorption Electrospray Ionization Mass Spectrometry (DESI) produces label-free, multiplexed and objective measurement of molecular targets from complex surfaces. This direct-from-sample analytical technique provides researchers with the spatially resolved molecular information needed to quickly and objectively interpret molecular profiles and understand mechanistic insights with confidence.

DESI is a soft ionization technique performed under ambient environmental conditions and requires no sample preparation. This direct tissue analysis provides non-subjective information about biochemical distribution of molecules after just one measurement.

Key features of DESI Imaging Techniques

• Ambient analysis technique to visualize the spatial localization and distribution of molecules
• No sample preparation. Collect molecular information directly from tissue samples
• Compatible with current histopathological workflows such as H&E Staining
• Measure small molecule drugs, lipid and endogenous metabolites