ACQUITY UPLC Technologies Fluidics modules matched with sub-2-μm hybrid particle columns to deliver superior chromatographic performance at higher pressures.

• QA/QC by quantification and by fingerprinting
• Quality control on raw material, TM extracts, and finished products
• Quality control of medicinal slices of TM
• Monitoring changes of key components during manufacturing processes.
• Batch-to-batch consistency, point of origin and condition changes, monitoring contaminants such as pesticides, key component quantification, and meeting regulatory requirements

ACQUITY UPC2 Technology Complementary to both GC and LC, convergence chromatography (CC) provides orthogonal and increased separation power using compressed carbon dioxide as the primary mobile phase to provide an exceptional increase in selectivity for your chromatographic laboratory.

• Separation and quantification of structural analogs, isomers, as well as enantiomeric and diasteriomeric compounds from plant extracts
• Profiling chemical ingredients with a wide range of polarity, including compounds with extremely high polarity from plant extracts (replacing normal phase LC)
• Profiling chemical ingredients with wide range of volatility including compounds that are highly volatile from plant extracts (replacing GC)

Purification Systems Premium customizable solutions for the entire purification range.

• Isolation of fractions that contain multiple components for high throughput screening, and for clinical studies in vitro and in vivo
• Isolation of reference standards and active metabolites crucial for natural product research
• Purification of chiral compounds, extremely polar compounds, and structurally similar TM compounds

Qualitative UPLC/MS & UPLC/MS/MS with Xevo G2-XS Tof, Xevo G2-S QTof, SYNAPT XS, and SYNAPT G2-Si HDMS Exact mass measurement time-of-flight and novel ion mobility solutions that allow for better, faster, and easier decisions.

• Sample profiling for identifying point of origin and condition changes
• Metabolomic/metabonomic studies for biomarkers and chemical markers
• Metabolite identification

Quantitative UPLC/MS/MS with Xevo TQ-XS, TQ-S micro, TQ-S cronos and Xevo TQD Innovative tandem quadrupole MS system engineered to provide superior performance and unparalleled usability.

• Quantification of trace-level ingredients from herbal extracts
• Quantitative DMPK studies, including bioanalysis and bioequivalence, for active ingredients from complex mixtures