This study presents the results of screening using a method based on UPLC in combination with Tof-MSE. The use of UPLC-Tof-MSE offers unique benefits for drug screening applications due to the acquisition of an unrestricted dataset with excellent sensitiv...

In this application note impurity identification of glipizide is characterized using UNIFI scientific information system platform.

To investigate the utility of the innovative data acquisition mode UPLC/MSe for the screening of toxicants in human urine.

The fruit of Lycium ruthenicum Murr. (LRF) has long been used in folk medicine. Nevertheless, detailed information related to its polyphenol compositions remains scarce.

This application note describes comprehensive analysis of impurities using UNIFI Scientific Information System.

This application note demonstrates the advantages of a UPLC/MSE method for characterization of protein digests. UPLC/MSE is a powerful tool that provides solutions for protein characterization challenges that are difficult to address with traditional pept...

This application note describes a reliable GC-MS method for screening and structural elucidation of non-intentionally added substances (NIAS) in food packaging materials.

This poster was presented at WCBP 2010, Jan 24-27 2010, in Washington D.C.

Biodegradable packagings are made by combination of several materials creating a multilayer with the properties needed. Each material, including the adhesive, could contain substances that could migrate to the food. In this work, gas chromatography couple...

Exposure studies involve complex data and subtle comparisons within the data sets. By utilizing the soft ionization of APGC and acquiring accurate mass data on both precursor and fragment ions in one method, a complete dataset can be produced.

This application note summarizes the collaboration between Vertex and Waters to test and demonstrate a quan/qual workflow to determine robustness and reliability of QTof measurements, and compare them against the gold-standard tandem quadrupole workflows.

Peptide mapping with UPLC/MSE improves the analytical efficiency of peptide characterization.

The aim of this study was to perform analysis of the GCF exudatome from healthy and periodontally diseased sites by LC/MSE, a label-free mass spectrometry method that enables simultaneous protein identification and absolute quantification in biological fl...

In this work, gas chromatography coupled with mass spectrometry and ultra-high-pressure liquid chromatography coupled with quadrupole time-of-flight mass spectrometry were used to identify the biodegradable adhesive compounds.

Data-independent acquisition (DIA) implemented in a method called MS(E) can be performed in a massively parallel, time-based schedule rather than by sampling masses sequentially in shotgun proteomics. In MSE alternating low and high energy spectra are col...

In this application note, we demonstrate the utility of UPLC/MSE for identification and quantification of covalent modifications in a yeast alcohol dehydrogenase (ADH) digest.

•Metabolome analysis for screening out six sulfur-fumigated markers. •Dissection of chemical transformation of sulfur-fumigated markers. •Times of the minimum content for evaluation of sulfur-fumigation. •Health risk assessment model for rational quality ...

This application note demonstrates the high sequence coverage for both heavy and light chains in the analysis of a monoclonal antibody by UPLC/MSE.