Waters offers a comprehensive range of analytical system solutions, software, and services for scientists. Liquid Chromatography. Mass Spectrometry. Waters is the leading provider of lab equipment, supplies and software for scientists across the world. Easily research and order everything your lab needs! Waters offers a comprehensive range of analytical system solutions, software, and services for scientists. Liquid Chromatography. Mass Spectrometry. Waters is the leading provider of lab equipment, supplies and software for scientists across the world. Easily research and order everything your lab needs!
Generation of Multiple Images from a Single Tissue Section with Dual Polarity Desorption Electrospray Ionization Mass Spectrometry
Here we demonstrate that by optimizing DESI imaging conditions, a wealth of molecular information can be accessed from a single tissue section. Multiple images containing unique information can be collected from a tissue sample without the need for the analysis of a number of serial sections.
The advantages of DESI imaging include:
- Optimization of DESI conditions allows multiple imaging experiments to be performed on the same tissue sample without altering the architecture or composition of the tissue
- Both positive and negative ion mode DESI imaging data can be collected from a single tissue section
- Using optimized DESI conditions enables subsequent analysis of tissue sections by other visualization techniques (i.e. H&E staining)
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