Screening for Classical and Novel Drugs in Pooled Urine Using UPLC-Tof-MSE

Library Number:
APNT134733981
Part Number:
720004583EN
Author(s):
John Archer, Paul Dargan, David Wood, Nayan Mistry, Michelle Wood
Source:
Waters Corporation
Content Type:
Application Notes
Content Subtype:
Application Notes
Related Products:
 
Toxicology

This study presents the results of screening using a method based on UPLC in combination with Tof-MSE. The use of UPLC-Tof-MSE offers unique benefits for drug screening applications due to the acquisition of an unrestricted dataset with excellent sensitivity. Accurate mass measurement allows the prediction of elemental composition, which is particluarly beneficial when dealing with situations involving potenetial emerging drugs and analogs.


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720004583en PDF 2250.05kB

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