Choosing an HPLC column can be a very difficult process. The Chromatographic Packing Material (Particle “Brand Name” and Functional group) plays a major role in the success of a separation, both initially, when the method is first developed, as well as long term, if the method will need to be reproduced for many years.
The US Pharmacopeia (USP) is a standard source for many pharmaceutical methods. The USP specifies columns by packing materials rather than by manufacturer. Listed here are the recommended Waters HPLC columns suitable for most LC methods listed with the USP.
If you do not know the brand of column you need, and you would like to learn more about HPLC column particle technology packing material, including better ways to choose packing materials for your application needs, visit www.waters.com/selectivitychart.