Increase Chromatographic Productivity and Reduce Solvent Consumption
The ACQUITY UPLC System allows scientists to obtain results in a more productive manner. This system consumes significantly less solvent than HPLC or monolithic stationary phases. A solvent savings of 82% can be achieved by moving to the UPLC method at the 2.1-mm scale; the solvent savings increases to 97% by moving to the UPLC method at the 1.0-mm scale. This adds up to tens of thousands of dollars per year in savings.
Acetonitrile Consumed Per Run Reduced from 10.50 mL to 0.53 mL
The transfer of a heterocyclic pharmaceutical QC assay from HPLC to UPLC reduced solvent consumption and disposal by an order of magnitude while improving chromatographic resolution and decreasing run time from 10 minutes to 1.5 minutes.
Solvent Consumption Down 85%
In a medicinal chemistry laboratory using open access UPLC Systems, solvent consumption decreased by 85%. Beyond the solvent savings, the lab manager reports, "I can offer my clients the same peak capacity in one-half the time."
Lowered Operational Costs by $30,000 Per Year
Within two months of implementation, the Open Architecture UPLC System performed 50% more analyses than the group's most used open access HPLC system. Their solvent consumption was reduced from 27.5 mL per analysis to just 1.9 mL. This reduction of approximately 150 L/year has led to a savings of over $30,000 in consumption and disposal costs.