Revolutionary Cyclic Ion Mobility

Ion mobility is an established technique in many applications and when coupled to mass spectrometry it provides:-

• The ability to separate on shape as well as m/z, enabling separation of isomers
• Significantly cleaner mass spectral data
• A measure of the ions Collisional Cross Section (CCS).

The circular path of the Cyclic Ion Mobility (cIM) device minimises instrument footprint whilst providing precise collisional cross section values (<0.5% RSD), multi pass variable, high resolution (>400) ion mobility separations and IMSⁿ.  The SELECT SERIES Cyclic IMS enables selection of ions by both mass and mobility which, is a unique and enabling functionality of cIM, providing unparalleled flexibility and capabilities for research studies in both academia and industry.

Discover more with ultimate ion mobility resolution

The instrument design and control software enables a range of experiments including acquisition of Tof data, Single pass ion mobility and the ability to scale mobility resolution to match the complexity of a sample.  Ion mobility resolution increases with the length of the mobility device and therefore with the number of passes.

Unlock the potential in scientific discovery

The unique instrument design facilitates advanced ion mobilty experiments.

IMSⁿ Selection - Extends the resolution of a specific mobility range e.g. ions of a specific species. Eject ions (without acquisition) outside of the desired mobility range. Leaving the remaining species in the cIM to continue the separation process. This ‘trimming’ approach can be undertaken numerous times and can be used, for example, to increase specificity of the selected ions or to prevent “wrap-around” in the cIM where high mobility ions catch up with low mobility ions in multi-pass experiments.

Undertake advanced structural characterization

IMSⁿ activation - During mobility separation a segment of the mobility separated species can be excised and these ions sent to the pre array storage device. Unwanted ions are ejected and stored ions are then re-injected into the array under collision induced dissociation conditions, as required, and subsequent mobility separation performed. The product ions can then be sent to the Tof for detection or can undergo further rounds of mobility selection providing the unique IMSⁿ capability.

Confidence in what you find

To complement the novel Cyclic Ion Mobility capability and for complete confidence in your data, the SELECT SERIES Cyclic IMS is equipped with the latest TOF technology.

The XS transfer device maintains the fidelity of the ion mobility separation whilst simultaneously conditioning the ion beam for the very best time-of-flight performance. The new offset oa-Tof with dual gain detection system provides improved sensitivity, resolution >100,000 (FWHM), reliable accurate exact mass measurements (low ppm) and improved dynamic range.

Take control

The new look MassLynx allows interactive control of the instrument and facilitates set-up of cyclic IMS methods, giving the user full control and allowing set-up of the sophisticated IMSⁿ experiments.  Mobility Miner data visualization software has been specifically designed to accommodate the data from the SELECT SERIES Cyclic IMS. This provides enhanced data visualization tools and data export functionality.  Importantly this software provides a platform for continued development to meet the increasing needs of mass spec experts.