Manage Your Physicochemical Property Analysis
The ProfileLynx™ Application Manager automates data processing for chromatography-based tests used in physicochemical property analyses for lead optimization. ProfileLynx manages your experimental setup, data processing, data review, and reporting for both LC/UV and LC/MS systems.
Conduct Retention Time Based and Quantitative Experiments
Compatible with both retention time based and quantitative experiments, ProfileLynx gives you the options to select from eight basic experimental types:
Retention Time-Based Experiments
- Chromatographic Hydrophobicity Index (CHI)
- Immobilized Artificial Membrane (IAM) Column Retention
- Column-Based Protein Binding
Quantitative Experiments
- Partitioning Coefficients
- Membrane Permeability
- Solubility
- Plate-Based Protein Binding
- Stability
Automate Processing and Acceptance Testing
ProfileLynx lets you define criteria for processing data from retention time and quantitation-based experiments:
- Set processing parameters such as peak extraction, detection, and integration parameters for the profile compounds as well as any internal standards being used
- Define maximum and minimum values for the physicochemical property indicators so that only the compounds within acceptable limits pass the test
Interactive Data Review
View your results in an interactive data review browser. Divided into three main areas, the browser provides a tabular summary of results, an interactive chromatogram window and the calibration curve used for physicochemical property calculation.
