Preparative-Scale SFC Purification

Waters' suite of bulk-scale SFC purification systems offer the optimal system for the amount of sample you need to purify. These systems easily allow you to purify a large amount of one sample.

Preparative Supercritical Fluid Chromatography 80q, 200q, and 350 are automated systems that feature co-solvent gradient, high-pressure separators for quantitative recovery of purified products, such as enantiomers, complex synthetic chemicals, and natural products. They are designed for chiral and achiral separations.

  SFC 80q SFC 200q SFC 350 
Optimal column I.D. 19 mm 30 mm 50 mm
Recommended total flow rate* 80 g/min 150 g/min 300 g/min
Typical throughput** Up to 15 g/day Up to 40 g/day Up to 100 g/day
Fractions 6 + 1 waste 5 + 1 waste 5 + 1 waste

*Under general operating conditions 1 g/min of CO2 is approximately equivalent to 1 mL/min

**Based on an 8 hour day

 


SFC 80q/200q and 350 Preparative Systems Waters SFC 80, 200, and 350 Preparative systems for bulk-scale purification offer the optimal system for the amount of sample you need to purify. These systems easily allow you to purify a large amount of one sample.
2489 UV/Visible (UV/Vis) Detector for Purification and Modular LC Systems A versatile, dual-wavelength absorbance detector that offers simplicity for routine UV-based applications and high sensitivity for low-level impurity analysis.
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