Integrate the versatility of Empower Software with the simplicity of Waters chromatography solutions for a flexible purification solution that will meet your laboratory's needs.

Waters' analytical to semi-preparative purification solutions are suitable for when you only have a limited number of samples to purify and don't need the advanced features of a full preparative system. These systems can sit on the end of the benchtop waiting for your chemists to use on-demand. These systems are optimal for when you want to purify micrograms to milligrams of your compounds.

Waters offers a full line of solvent delivery systems capable of delivering flow rates up to 300 mL/min.

Sample and Solvent Management:

• With either manual or automated injection capability, system configurations can vary by throughput and scale requirements
• Flexible injection capabilities with manual and automated injection
• Flexible solvent delivery capabilities with flow rates up to 300 mL/min
• User-friendly console and software features help you manage solvents and samples, whether you do manual or automated injections
• Proprietary Optimum Bed Density (OBD) Column design offers the highest sample loading and unmatched column stability

Fraction Collection:

• The Waters Fraction Collector III is a compact, flexible and easy-to-use collector
• Flexible collection formats
• Designed for use in both small-scale and large-scale work environments
• Easily integrates with many Waters system configurations

Detection:

• UV-Vis
• Photodiode Array (PDA)
• Evaporative Light Scattering (ELS)
• Or any detector capable of delivering an analog signal to the collector

Make common preparative chromatography calculations with the Preparative OBD Column Calculator.

From acquisition to real-time monitoring and total results management, you’ll never be more than a few clicks away from the purification answers you are looking for. You can now perform fraction collection using either Empower Software or MassLynx Software and its FractionLynx Application Manager.

Integrated Operation with Empower Software

Control of the Waters Fraction Collector III is available through a new instrument interface using Empower Software. Once the instrument control software (ICS) has been loaded, the interface integrates seamlessly with existing Empower control components. The collector control software enables the user to configure collection vessels and program collection routines. Real-time feedback from the fraction collector indicates the state of the collection process and the location of the collected fractions.

Integrated control panels with Empower Software offer consistent instrument operation.

Collection Control

The collection control interface allows the operator to perform different collection techniques:

• Collection of everything with time slicing
• Time-based collection of specific segments of the run
• Collection of eluent between triggered fractions
• Detector-triggered collection based on:
• Threshold
• Slope
• Slope and threshold

When large-volume samples require repetitive injections to be made and the fractions collected repeatedly into the same container, the collection protocol simply requires a single box to be checked in order to perform this task.

For low-flow applications, the operator can choose not to open and close the diverter valve between consecutive fractions, and so not run the risk of diverting valuable segments of sample to waste.

Fraction collection information is embedded into Empower Software datasets and is available in a comprehensive report. The report can be viewed in an electronic format and saved to the database.