Waters MassTrak clinical solution integrates liquid chromatography (LC), mass spectrometry (MS), software, reagents, and support services.

MassTrak Immunosuppressants Kit

The Waters MassTrak Immunosuppressants kit is designed to provide quantitative analysis of Tacrolimus in the whole blood of kidney and liver transplant recipients. This LC/MS/MS based solution may eliminate issues known to occur with the Tacrolimus immunoassays namely cross reactivity, poor precision and inaccuracies due to hematocrit variability.

• The Immunosuppressant solution is a total system solution incorporating the ACQUITY UPLC and MS platform with software and pre-packaged, fully tested reagents and consumables from Waters.
• Installation services as well as dedicated support and training services from Waters enables the fastest possible start-up and continued success in your laboratory.
• The MassTrak kit delivers excellent specificity and sensitivity may improve both accuracy and precision of reported values compared to immunoassay.
• Your laboratory can help increase the quality, results and throughput of the assays performed, using the latest technology cost effectively.
• For additional MassTrak TDM C₁₈ Columns, call your local sales representative.

For in vitro diagnostic use. Not available in all countries. For information on availability, please contact your local representative.

Tacrolimus Monitoring - MassTrak^TM LC/MS/MS

• The MassTrak^TM Immunosuppressants kit is 510(k) cleared and CE Marked for the quantification of Tacrolimus in kidney and liver transplant patients whole blood samples as an aid in the management of Tacrolimus therapy.
• The total solution is available incorporating instrument, software, methodology and validated reagent kit.

Waters provides comprehensive

• Application expertise and Field Services
• Instrument Repairs
• Application specific telephone support
• Remote diagnostic and monitoring capabilities
• Application specific installation and start up training

Your laboratory realizes

• Faster through put with reliable results
• Minimized down time
• An attractive ROI

The MassTrak Immunosuppressant Kit is FDA cleared and CE marked per 28/79/EC directive for in vitro diagnostic use and is designed for use in clinical laboratories by professionally trained staff.

Ordering information

MassTrak Immunosuppressant kit 176000898 (includes reagents and column to perform up to 500 tests).  The kit is designed for use with a Waters tandem quadrupole mass spectrometer and a Waters gradient liquid chromatograph. Other MS/MS or LC systems may require modification and verification of the instrument parameters for optimum performance. This kit has been optimized on the following configuration a Waters Quattro micro™ tandem mass spectrometer coupled to an Alliance 2795 LC system. Waters Sentry™ 2.1 x 10 mm cartridge holder (part number WAT097958) is not included in the kit but is required for operation of the MassTrak TDM C18 guard column.

The MassTrak Immunosuppressant Kit is for in vitro diagnostic use and is designed for use in clinical laboratories by professionally trained staff.

Instrument configurations

The MassTrak Immunosuppressant Kit can be used with the following Waters instrumentation

• Waters Quattro micro™ tandem mass spectrometer coupled to an Alliance 2795   LC system.
• ACQUITY TQD operated in conjunction with an ACQUITY UPLC

The MassTrak Immunosuppressant Kit is FDA cleared and CE marked per 28/79/EC directive for in vitro diagnostic use and is designed for use in clinical laboratories by professionally trained staff.

Be assured. Choose Waters Global Services

For nearly 50 years, Waters Global Services has focused exclusively on optimizing Waters products with superior service, support, training, and Waters Quality Parts®. Only the Waters service team has the most in-depth and up-to-date knowledge of the advanced science and technologies that provide the foundation for Waters systems. This enables Waters to help you maximize system uptime, increase laboratory productivity, and meet compliance requirements. With more than 94 offices in 50 countries, Waters maintains a strong global presence. Whether your company is a single-location lab or a large multinational organization, we offer support whenever and wherever you need it.

A program of specific support is offered to clinical laboratories. This support includes:

• guaranteed priority service
• guaranteed two hour response for call back after receipt of a support call
• guaranteed on-site response time of two business days (48) hours
• single vendor support for HPLC and mass spectrometry and applications
• optional remote monitoring and diagnostic capabilities

The MassTrak Immunosuppressant Kit is FDA cleared and CE marked per 28/79/EC directive for in vitro diagnostic use and is designed for use in clinical laboratories by professionally trained staff.

Figure 1 shows a representative chromatogram of tacrolimus