The ability to reproducibly generate high quality peptide separations is of critical importance in proteomics research as well as for the characterization of biopharmaceuticals via peptide mapping. Waters Ethylene Bridged Hybrid (BEH) and Charged Surface Hybrid (CSH™) technologies provide stable and reproducible peptide separations. They are available in a wide range of particle, pore and column sizes for analytical and lab-scale purifications. Waters separation technologies provide narrow, symmetrical peaks for best resolution and successfully separate a wide range of peptides: large and small, acidic and basic, hydrophobic and hydrophilic.