Natural Products and Traditional Medicines Solutions

Natural Products and Traditional Medicines Solutions

Traditional medicines and active ingredients in natural products hold many mysteries. The potency of specific herbs is largely unknown, and research efforts to understand the complex interactions between components and their precise pharmacological mechanisms that benefit patients in clinical treatment is critical. Waters offers the expertise, sophisticated analytical solutions, and support to overcome your analytical challenges with traditional medicines.

Traditional medicines and active ingredients in natural products hold many mysteries. The potency of specific herbs is largely unknown, and research efforts to understand the complex interactions between components and their precise pharmacological mechanisms that benefit patients in clinical treatment is critical. Waters offers the expertise, sophisticated analytical solutions, and support to overcome your analytical challenges with traditional medicines.
Traditional chinese herbal medicine with pestle bowl
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Overview

Traditional medicine holds many wonders and many mysteries. Analytical laboratories strive to understand their pharmacology in hopes of obtaining evidence-based validation of effectiveness and establishing safe production guidelines.

Today, standard analytical techniques are being used more and more often across a variety of tasks, from screening to sample profiling to QA/QC. Waters can provide the high-quality separations and detection capabilities necessary to identify active compounds and chemical ingredients in highly complex samples. The Waters workflow-based approach, combined with user-friendly software, enables you to quickly perform sample analysis and obtain maximum information.

Applications

There has been a tremendous increase in traditional medicines and natural products for health benefits and therapeutic effects. Learn how Waters helps you quickly perform sample analysis and obtain maximum information.

There has been a tremendous increase in traditional medicines and natural products for health benefits and therapeutic effects. Learn how Waters helps you quickly perform sample analysis and obtain maximum information.

Application Notes

Many active ingredients discovered from natural products have become dietary supplements and represent a multibillion dollar global market. The popularity of these products brings a need to ensure that label claims are met, and that supplement composition and formulation is well characterized.

Many active ingredients discovered from natural products have become dietary supplements and represent a multibillion dollar global market. The popularity of these products brings a need to ensure that label claims are met, and that supplement composition and formulation is well characterized.

Application Notes

Solutions

With Waters systems, techniques such as purification, qualitative, and quantitative chromatography and mass spectrometry are applied to determine the efficacy of traditional herbal medicines.

With Waters systems, techniques such as purification, qualitative, and quantitative chromatography and mass spectrometry are applied to determine the efficacy of traditional herbal medicines.

The next evolution in separation science is here

The next evolution in separation science is here
ACQUITY Premier System

Maximize the sensitivity, repeatability and robustness of your LC and LC-MS applications with the ACQUITY Premier System, delivering superior chromatographic performance, lab efficiency and risk control.

  • QA/QC by quantification and by fingerprinting

  • Quality control on raw material, traditional medicine extracts, and finished products 

  • Quality control of medicinal slices of traditional medicine

  • Monitoring changes of key components during manufacturing processes

  • Batch-to-batch consistency, point of origin and condition changes, monitoring contaminants such as pesticides, key component quantification, and meeting regulatory requirements 

  • Food
  • Pharmaceutical

The ease of reversed-phase meets the power of normal-phase

The ease of reversed-phase meets the power of normal-phase
ACQUITY UPC2 System

ACQUITY UPC2 technology complementary to both GC and LC and convergence chromatography provides orthogonal and increased separation power using compressed carbon dioxide as the primary mobile phase for enhancing selectivity in laboratory.

  • Separation and quantification of structural analogs, isomers, as well as enantiomeric and diasteriomeric compounds from plant extracts

  • Profiling chemical ingredients with a wide range of polarity, including compounds with extremely high polarity from plant extracts (replacing normal phase LC)

  • Profiling chemical ingredients with wide range of volatility including compounds that are highly volatile from plant extracts (replacing GC) 

  • Food
  • Pharmaceutical

Endless possibilities. Limitless research.

Endless possibilities. Limitless research.
SELECT SERIES Cyclic IMS

Separate ions by shape and m/z with the Cyclic IMS, combining cyclic ion mobility with time-of-flight (Tof) technology for separating isomers, measuring the Collisional Cross Section (CCS) of an ion, and achieving cleaner mass spectral data.

  • Food
  • Pharmaceutical

Redefine performance with all the benefits of time-of-flight technology

Redefine performance with all the benefits of time-of-flight technology
SELECT SERIES MRT

Accelerate your research and achieve groundbreaking time-of-flight (Tof) resolution with the SELECT SERIES MRT and embrace the future of high-resolution mass spectrometry.

  • Food
  • Pharmaceutical

Achieve ultimate flexibility for deeper discovery

Achieve ultimate flexibility for deeper discovery
SYNAPT XS HDMS

Obtain the ultimate flexibility and greater freedom of analytical choice to support scientific creativity and technical success for any application with Waters SYNAPT XS HDMS.

  • Food
  • Pharmaceutical

Complete coverage for confident characterization

Complete coverage for confident characterization
Xevo G3 QTof

Maximize sample information for your analytes from detailed characterization to accurate quantitation with the Xevo G3 QTof, which enables complete confidence in your results.

  • Food
  • Pharmaceutical

Delivering exceptional performance and unmatched usability

Delivering exceptional performance and unmatched usability
Tandem Quadrupole Mass Spectrometry Systems

Waters quantitative UPLC-MS/MS systems are innovative tandem quadrupole MS systems thoughtfully designed to deliver superior performance and unparalleled usability. With Waters tandem quad systems, your lab can analyze:

  • Quantification of trace-level ingredients from herbal extracts 

  • Quantitative DMPK studies, including bioanalysis and bioequivalence, for active ingredients from complex mixtures

  • Food
  • Pharmaceutical

Delivering SmartMS to the masses

Delivering SmartMS to the masses
ACQUITY RDa Detector

Increase productivity, improve data confidence, and simplify routine accurate mass workflows with the compact, compliance-ready and easy-to-use ACQUITY RDa Detector, ideal for ensuring your entire laboratory can easily access high-resolution mass measurements.

  • Food
  • Pharmaceutical

Accelerate your digital journey with Waters lab management software, streamlining your workflows for informed decision-making.

Accelerate your digital journey with Waters lab management software, streamlining your workflows for informed decision-making.

Accurately quantify, identify, and confidently analyze complex LC-MS data

Accurately quantify, identify, and confidently analyze complex LC-MS data
Progenesis QI

Use Progenesis QI Software to analyze your LC-MS data effectively. This software enables your lab to quantify and then identify the small molecules, lipids, and proteins that are significantly changing in your samples.

  • Food
  • Pharmaceutical

Maximize method performance and achieve business productivity and profitability with Waters portfolio of columns and consumables.

Maximize method performance and achieve business productivity and profitability with Waters portfolio of columns and consumables.

Ensure premier performance for all analytes

Ensure premier performance for all analytes
ACQUITY Premier Columns

With Waters ACQUITY Premier Columns, chromatographers can harness the separation efficiency improvements and increased flow rates of UPLC technology, improving analyte resolution, sensitivity, business productivity, and profitability.

  • Food
  • Pharmaceutical

Achieve accurate results for several forensic screening, confirmation, and quantitation workflows using streamlined Waters analytical services.

Achieve accurate results for several forensic screening, confirmation, and quantitation workflows using streamlined Waters analytical services.

Your success is just a click away

Your success is just a click away
Waters Global Services

Optimize your laboratory's productivity while addressing your budget realities with Waters Global Services. Maintain peak system performance, minimize down time, address scientific application challenges, and support stringent compliance requirements.

  • Food
  • Pharmaceutical

Make science more accessible with Waters Capital

Make science more accessible with Waters Capital
Payment Solutions

Maximize resources and minimize risk with payment options from Waters Capital, including upgrading aging equipment, getting customized support, and bundling services into one monthly payment.

  • Food
  • Pharmaceutical

The data speaks for itself

The data speaks for itself
UPC2-MS chromatograms of the mixtures obtained by (A) SFE and (B) methanol extraction, using on ACQUITY UPC2-EP Column.
The Traditional Medicine Library's infrastructure links each compound to its plants of origin and chemical classes. By standardizing analytic lab processes across laboratories, it helps to expedite research progress and development decisions.
RADAR technology allows for simultaneous acquisition of MRM and full scan data in a single analysis run. Spectrum identifying untargeted contaminants in sample matrix are shown in the insert of the full scan data.

Webinars and Resources

  • On Demand Webinar

How Can Metabolomics Accelerate Natural Product Discovery?

How Can Metabolomics Accelerate Natural Product Discovery?
Watch

Related

Life Science Research
For biomedical research and biomarker discovery solutions via LC-MS applications, Waters has the chromatography systems, informatics and resources you need to be successful.

Biopharma and Pharma
Waters accessible yet powerful analytical workflow solutions translate complexity into clarity, so you can efficiently access the knowledge to take your product from Point A to Point FDA, EMA, and beyond.

Learn more about Natural Products and Traditional Medicines Solutions.

Learn more about Natural Products and Traditional Medicines Solutions.
Traditional chinese herbal medicine with pestle bowl
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