ACQUITY Arc System
HPLC and UHPLC method compatibility at the flip of a switch
The ACQUITY Arc System is a quaternary-based, modern LC system for scientists working with established methods who are looking for the versatility and robustness required to bridge the gap between HPLC and UHPLC while continuing to support validated assays.
- Achieve both HPLC and UHPLC separations in one instrument with regulatory compliant-ready hardware and software
- Boost the chromatographic performance of your methods with the benefits of 2.x μm particle columns
- Eliminate the cumbersome and error-prone approach of manual preparation with on-demand mobile phase creation with Auto●Blend Plus Technology
- Adjust for differences in dwell volume between systems to achieve repeatability between systems with the combination of the dual-flow paths and Gradient SmartStart
ACQUITY Arc System
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Specifications
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Maximum operating pressure |
9500 psi |
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pH range* |
1–12.5 |
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Operating flow rate range |
Up to 5 mL/min |
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Sample flow path |
Stainless-steel |
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Sample carryover |
≤0.002% (Caffeine) under UV conditions |
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Sample compartment |
4–40 °C |
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Pump options |
Quaternary |
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Solvent conditioning |
Passive and active pre-heating |
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Column tracking |
eCord Technology column information tracks and archives column usage |
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Column capacity |
Up to 15 columns of 150 mm length and up to 4.6 mm I.D. |
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Maximum sample capacity |
Up to 20 plates (with Sample Organizer) |
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Detector options |
TUV Detector PDA Detector FLR Detector RI Detector ELS Detector EC Detector |
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External control |
Empower Software MassLynx Software |
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Physical specifications (QSM-R or BSM-R, SM-FTN-R, 30cm CH) |
Width: 34.3 cm (13.5 in.) Height: 71.1 cm (28.0 in.) Depth: 71.2 cm (28.0 in.) |
Overview
- Go from HPLC to UHPLC with the flip of a switch - Easily switch between HPLC and UHPLC operation with multi-flow technology to select the dwell volume that fits best the column separation.
- Simplify your daily set-up - Fully automate your daily system start-up, including system priming and equilibration, with Empower 3 Software. Get real-time information on all of system components in one location, with a simple and intuitive interface using the ACQUITY Console.
- Speed mobile phase preparation with more repeatability - Reduce the time it takes to prepare mobile phases while improving the day-to-day repeatability of your preparations by preparing your pH buffers online from pure solvents with Auto●Blend Plus Technology.
- Minimize carryover - Achieve ultra-low carryover (≤0.002%) by continuously cleansing the needle during the run with an advanced flow-through-needle design.
- Achieve flexibility and stability for method development - Column manager options available for up to 15 columns ranging in length from 50 mm to 300 mm with a temperature range of 4 °C to 90 °C. Optional and integrated column selection valve provide fast, unattended column changeover.
- Provide stability for method transfer needs - Provide stable, uniform temperature management with integrated active pre-heating options to ensure method repeatability from lab to lab. Gradient SmartStart easily adjusts for system volume differences when transferring methods from an alternative LC system without alteration to the method table.
Recommended Use: For modernizing your chromatography while being able to run legacy, validated methods.
Features Header
Replicate your established methods
Get seamless and efficient transfer, adjustment, or improvement of methods from any LC platform without compromise in method integrity or changes to validated gradient tables with the ACQUITY Arc System.
The ACQUITY Arc System can replicate your established HPLC methods by compensating for these differences with unique features such as the Arc multi-flow path technology and Gradient SmartStart. With these innovative attributes, you can seamlessly replicate your existing chromatographic results to meet your acceptance criteria without changes to validated gradient tables.
Go from HPLC to UHPLC with the flip of a switch
With the multi-flow path technology in the ACQUITY Arc System, you can easily switch between HPLC and UHPLC operation by selecting the dwell volume that best fits the column separation. The ACQUITY Arc System’s reliability and robustness ensures product consistency and compliance with regulatory guidelines, all while minimizing downtime and inefficiencies.
With the ACQUITY Arc System, you can maximize productivity by combining system dispersion characteristics with efficient and rapid 2.x µm UHPLC separations or larger, 3.0–5.0 µm particles - so you get the flexibility your lab needs to support a wide-range of LC applications.
Simplify your daily set-up
Improve your laboratory workflow with the advanced software capabilities included with the ACQUITY Arc System.
- Fully automate your daily system start-up, including system priming and equilibration, with Empower 3 Software.
- Get real-time information on all of system components in one location with a simple and intuitive interface using ACQUITY Console.
- Prepare your pH buffers online from pure solvents, significantly reducing the time it takes to prepare mobile phases while improving the day-to-day repeatability of your preparations with Auto●Blend Plus technology.
Develop methods that stand the test of time
Need an orthogonal detection approach to UV in your method development? Streamline your method development with an LC-MS solution that’s as easy to use as photodiode array detection.
The ACQUITY Arc System is fully compatible with the ACQUITY QDa Mass Detector, supporting efficient and robust method development by expanding the information you can get from your system using the same Empower Software. The system automatically pairs qualitative mass spectral data to the peaks in your chromatogram, leaving nothing to chance.
Confirm the identity of peaks in a separation without injecting standards
Identify new peaks in a separation with molecular weight information
Detect unresolved peaks and determine if a peak is homogenously pure
Easily track peaks as method conditions are changed
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