ACQUITY APC Columns
Achieve superior speed and resolution for polymer characterization
Achieving superior performance and reliability with high resolution polymer characterization can be a challenge. ACQUITY Advanced Polymer Chromatography (APC) Columns are designed for polymer scientists like you, with novel capabilities for chromatographic efficiency, speed and resolution that cannot be matched by conventional GPC methods. With these columns, you can quantify and characterize polymer samples with confidence and accuracy while maximizing productivity.
The Ethylene Bridged Hybrid (BEH) particles used in ACQUITY APC Columns enable rapid solvent switching and the ability to use multiple conditions for the same bank of columns. Conventional polymeric stationary phases are dedicated to a single set of analytical conditions and solvent because the chromatographic bed is vulnerable to shrinking and swelling. By eliminating this undesirable behavior, ACQUITY APC Columns allow for maximum robustness and method development flexibility.
ACQUITY APC Columns
Specifications
Overview
- Eliminate the shrinking and swelling that often occurs with polymeric stationary phases upon solvent switching with a stable chromatographic column bed
- Achieve unmatched separation speed, resolution, and chromatographic efficiency from optimized pore volumes and particle size
- Meet workflow requirements with 1.7 and 2.5 μm columns for organic and aqueous size-based separation
- Achieve industry-leading column-to-column reproducibility with exceptionally reliable columns from a tightly controlled column manufacturing process
Recommended Use: For rapid and accurate chromatographic characterization of synthetic polymer and macromolecular species.
ACQUITY APC Column Featured Technologies
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Rugged hybrid organic/inorganic base particle -
Improved peak shape for bases- low silanol activity
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Wider operating pH range for method development flexibility
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Mechanical strength for maximum column efficiency at UHPLC operating pressures
ACQUITY APC Column Characteristics
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Designed to provide high efficiency sized-based separations for organic soluble polymer characterization
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Uses BEH particle technology
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Stable column bed that resists shrinking and swelling for easy mobile-phase solvent switching
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Features an extended temperature range up to 90 °C
Designed for organic solvent-based separations
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Designed to provide high efficiency sized-based separations for water soluble polymer characterization
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Uses BEH particle technology
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Robust separations up to 45 °C
Designed for aqueous-soluble polymer separations
Unprecedented capacity for rapid solvent switching
Use multiple conditions for the same column bank with rapid solvent switching using the rigid hybrid particles in ACQUITY APC Chromatography Columns. Conventional polymeric phases are often dedicated to single analysis conditions because the chromatographic bed is vulnerable to shrinking and swelling that can be potentially harmful to the column. By eliminating this constraint, ACQUITY APC Chromatography Columns provide more freedom for method development and deliver advanced polymer characterization for a diverse range of samples.
Reduce calibration time by a factor of 3-5x and increase resolution
With long conventional Gel Permeation Chromatography (GPC) run times of up to one hour or more, analyses of standards and samples can be quite time-consuming. In addition to long GPC run times, the large extra-column volume of conventional GPC systems can result in peak bandspreading, reducing the resolution and thus accuracy of the calibration points. Combined with the lower dispersion ACQUITY APC System, small particle ACQUITY APC Columns deliver less bandspreading and narrower, sharper peaks compared to the conventional GPC system. Additionally, robust sub-3-µm APC Column Technology supports higher flow rate and backpressures, thereby improving resolution.
Ensure reproducible column performance
Reproducible column performance is one of the most critical factors for achieving long-term method reliability during polymer characterization. Each step of our column manufacturing process is monitored and tightly controlled to maintain unmatched product reproducibility. Every test, from raw material characterization to final batch analysis, is designed to ensure that ACQUITY APC Columns perform the same from column-to-column, batch-to-batch, and year-to-year.
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