Do You See What We See? Mass Spectrometry Imaging is Revealing Insights in Biomedical Research

The spatial distribution of molecular species in a sample can provide a wealth of information about biological, chemical and physiological processes. Mass spectrometry (MS) imaging is a rapidly developing research technique that enables specific measurement of molecular targets at complex surfaces. This direct-from-sample analytical technique provides researchers with the information needed to quickly and objectively interpret molecular profiles and make confident decisions based on definitive data.

Waters’ advanced MS imaging technology includes Matrix Assisted Laser Desorption Ionization (MALDI), Desorption Electrospray Ionization (DESI), and ion mobility separations.

At the American Society for Mass Spectrometry (ASMS) conference in San Antonio (June 6-10), Waters’ scientists and our collaborators demonstrated the utility of MS imaging across a range of applications such as proteomics, metabolomics, cell and tissue biology, research pathology, and histology, and showcased the latest technical developments in these exciting technologies.

Here are our featured posters:

• DESI Imaging at Varying Acquisition Rates with Real Time Imaging Display for Optimized Tissue Imaging
• Automating High Throughput 3D Imaging Using DESI Mass Spectrometry
• Investigation into the Use of Tissue Washing Procedures and the Subsequent Outcomes for DESI-MS Imaging Analyses

To learn more about the power of MS imaging and ion mobility, check out the latest video series by Jose Castro-Perez, Ph.D., director of Health Sciences Marketing for Waters, where he presents a thorough overview of this rapidly growing technique and how it is being used in the mass spectrometry, biomedical, and pathology scientific communities.