Is Your Biomedical Research Accurate and Precise?

Is Your Biomedical Research Accurate and Precise?

In biomedical research, scientists need the ability to accurately and precisely measure a biomarker or set of biomarkers in some disease vs. healthy experimental design. The ability to measure something depends on the ability of the measurement methodology, including analytical tools, to accurately and precisely quantify the true value for the object of interest. Accuracy:…

Mass Spectrometry Makes Cents for UC San Diego Clinical Laboratory

Mass Spectrometry Makes Cents for UC San Diego Clinical Laboratory

“Fast is fine; but accuracy is everything.” The quote is attributed to the famous Wyatt Earp, a sharpshooter and lawman who, with help from his two brothers, sent three outlaws to their graves in the Gunfight at the O.K. Corral in Tombstone, Arizona in 1881. One hundred and twenty five years later, Dr. Rob Fitzgerald…

Molecular Visualization: Mass Spec Imaging Delivers Insights for Cancer Research

Molecular Visualization: Mass Spec Imaging Delivers Insights for Cancer Research

How does mass spectrometry (MS) imaging provide a molecular image that can be used for the biochemical characterization of histological images? A rapidly developing technique for clinical research, MS imaging enables investigation of the spatial distribution of molecules at complex surfaces. It’s a direct-from-sample analytical technique that provides researchers with the information needed to quickly…

Can Sports Cars Increase Testosterone?

Can Sports Cars Increase Testosterone?

According to published reports by Hiscox UK in 2008,  just listening to the sound of a sports car increased salivary testosterone levels in male and female participants. Another study, by Gad Saad et al, measured a testosterone increase in men who were given the opportunity to drive a $150,000 Porsche 911 Carrera Cabriolet for an…

Laboratory Developed Tests: More Oversight, or More Vigilance and Reporting?

Laboratory Developed Tests: More Oversight, or More Vigilance and Reporting?

U.S. FDA Prepares to Oversee LDTs Recently, the U.S. Food and Drug Administration’s Office of Public Health Strategy and Analysis issued an interesting (and much anticipated) report regarding Laboratory Developed Tests (LDTs). The Agency has consistently cited a need for greater oversight of LDTs out of concern for public safety. Laboratory Developed Tests used to…