New Preparative Chromatography Learning Tool: Peptide Isolation Primer

As the interest in peptides as potential drug candidates increases, the need for basic information about the isolation and purification of these peptides also grows.

New Preparative Chromatography Learning Tool: SFC Primer

In recent years, many laboratories have begun to include Supercritical Fluid Chromatography (SFC) as part of their purification strategies. Learn the basics of SFC in our primer.

A Leading CRO’s Customer Focus Leads to Improvements in Quality and Productivity

“One of the important reasons that we use Waters LC-MS instruments is that beyond the quality of the products, Waters delivers a high degree of technical training. This provides us with the knowledge and confidence that we can solve our complex research questions.” comments Triskelion’s Richard Bas.

Infographic: Simplifying the Screening Workflow for Extractables Testing

How to design an analytical workflow to screen for extractables and leachables The safety of pharmaceuticals, cosmetics, and foodstuffs may be compromised by chemical compounds in the various types of packaging and food contact materials (FCMs) that are in direct contact with the consumer product. Due to continuously increasing global regulations, the characterization of extractables…

Infographic: Large Molecules Have a 2X Greater FDA Approval Rate Than Small Molecule Drugs

It’s no surprise that pharma is ‘Thinking Large’ Large molecules are dominating pharma sales and FDA approvals. At the end of 2015, seven of the top 10 best-selling prescription drugs were large molecules. According to a 2014 article in Nature, the overall approval rate for small and large molecule therapeutics is nearly 10% (comprised of lead and secondary…

Tips to maintain your HPLC & UHPLC systems and columns

Recently, Ade Kujore (Cecil Instruments), Tracie Brombos (GenTech Scientific), and I were asked by Angelo De Palma, a well-respected writer for Lab Manager magazine, to contribute to an article about maintaining and caring for your laboratory instruments. Here are my tips and best practices for column and HPLC, UHLPC, and UPLC system maintenance. Maintaining your…

The Waters ACQUITY Arc System Receives 2016 Frost & Sullivan New Product Innovation Award

Bridging the gap between HPLC and UPLC performance, the ACQUITY Arc System is a favorite of QC laboratories that test small and large molecule pharmaceuticals. We’re excited to announce today (Tuesday, Oct. 5) that our ACQUITY® Arc™ System has just received a 2016 New Product Innovation Award from market research and growth consulting firm Frost…

Waters and BioanalysisZone are Highlighting our Bioanalytical Chemists

Like the black panther, are analytical scientists going extinct? In a presidential election year, we are reminded of the many tough choices we face—Democrats or Republicans, plastic or paper, ketchup or mustard, soccer or football. And as we watched the Olympic track and field events, for instance, we saw the margin between first and last…

Is using Microflow LC in an Industrial Setting Really that Cumbersome?

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Microflow or nanoflow chromatography has been used mostly in the academic and fundamental research environment in the past for its various advantages over analytical liquid chromatography, but rarely in the industrial settings. This is most likely because many of us believe it is a pain-in-the-neck technique to perform! But is this a reality or just…

Good Scent. Bad Reaction?

A New Approach for Detecting Fragrance Allergens Have you ever sat next to someone wearing heavy cologne and suddenly noticed that your eyes were watering? Hopefully, you’ve never had that experience, but if you have (I actually have), then there’s a good possibility that you have had an allergic reaction to something in the perfume….

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What Bioanalysis Zone’s New Investigator Award Says About the Future of Science: An Interview with Erin Chambers, PhD

Dr. Erin Chambers is a Director in the Scientific Operations group at Waters Corporation. She recently served as a judge for the Bioanalysis Zone New Investigator Award. I sat down with Erin to gauge her impressions of that experience and the award’s importance to the bioanalysis industry. What was it like to be part of…

Method Scaling in Preparative HPLC: Analytical Method &
Preparative Method

Andrew Aubin (Andy): Manager, Purification / SFx Systems Marketing Laboratory & Blogger VOC: Voice of the Chemist VOC:  “I tried to scale up my analytical HPLC method to prep and it didn’t work.” Andy:  This is one of the most common things we hear from chemists wanting to do preparative chromatography. We also hear the following…